James was named NBA's Eastern Conference Player of the Week for games played Monday, February 18 through Sunday, February 24. It was the third time he has won the award this season and the 13th time he has won the award in his career. On February 27, 2008, against the Boston Celtics, James became the youngest person to score 10,000 points in his career at 23 years and 59 days, achieving the feat in style with a slam-dunk over 11-time All-Star Kevin Garnett, eclipsing the old mark by more than a year. James did so in 368 games, the ninth fastest in league history.
On March 3, 2008 James was named the Eastern Conference Player of the Month for February 2008. It was the second straight month that he won the award. On March 5, 2008, James scored 50 points with 8 rebounds and 10 assists on the New York Knicks, becoming only the third player since the NBA-ABA merger to record a 50-point 10-assist game. On March 10, 2008, James notched his seventh triple double of the season against the Portland Trail Blazers. Seven triple doubles in a season broke his personal and team records for triple doubles in a season and 17 career triple doubles broke his team record as well. On March 12, 2008, James scored 42 points against the New Jersey Nets and surpassed Austin Carr for second all-time in Cavaliers points scored. On March 21, 2008, James scored 29 points against the Toronto Raptors, taking him past Brad Daugherty's all-time Cavaliers scoring record of 10,389 points. Daugherty achieved this record over the course of 548 games, while James took only 380 games to score 10,414 points.
All told, James had propelled Cleveland to a 45–37 record, good for second place in the Central Division and the 4th seed in the Eastern Conference Playoffs. Prior to Cleveland's first-round series versus the Washington Wizards, Wizards guard Deshawn Stevenson said James was "overrated," prompting James to say that he would not return the insult, as that would be "almost like Jay-Z [responding to a negative comment] made by Soulja Boy." In response, Soulja Boy himself made an appearance at Game 3 of the series (played in Washington) in support of the Wizards, and his music was played over the PA system. James would later say that he meant no disrespect to Soulja Boy with his comment, and that his young son is a big fan of the rapper. Jay-Z responded by producing a freestyle version of the Too Short single "Blow the Whistle", named "Playoff", in which he "disses" Stevenson and Soulja Boy on James' behalf.. The Cavaliers would go on and win the series in 6 games (4–2), setting up a meeting with the Boston Celtics. The series was decided by the seventh game in Boston. James and opponent Paul Pierce each scored 40+ points, but the Cavaliers could not get a victory, thus losing the series (4–3).